PIPERAZINE-2-CARBOXAMIDE

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PIPERAZINE-2-CARBOXAMIDE

  • Name PIPERAZINE-2-CARBOXAMIDE
  • CAS 84501-64-4
  • Purity 99%
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Product Details

Quality Factory Supply 99% Pure PIPERAZINE-2-CARBOXAMIDE 84501-64-4 with Efficient Delivery

  • Molecular Formula: C5H11N3O
  • Molecular Weight: 129.162
  • Vapor Pressure: 1.72E-05mmHg at 25°C 
  • Melting Point: 144-145 °C(Solv: ethanol (64-17-5)) 
  • Refractive Index: 1.48 
  • Boiling Point: 364.2 °C at 760 mmHg 
  • PKA: 16.52±0.20(Predicted) 
  • Flash Point: 174 °C 
  • PSA: 67.15000 
  • Density: 1.104 g/cm3 
  • LogP: -0.60900 

PIPERAZINE-2-CARBOXAMIDE(Cas 84501-64-4) Usage

General Description

PIPERAZINE-2-CARBOXAMIDE, also known as piperazine amide, is a chemical compound with the molecular formula C6H10N4O. It is a white crystalline powder that is soluble in water and alcohol. PIPERAZINE-2-CARBOXAMIDE is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs, including antihistamines, antipsychotics, and antimalarial agents. It acts as a building block in the production of these medications, contributing to their therapeutic effects. Additionally, PIPERAZINE-2-CARBOXAMIDE is used in the research and development of new pharmaceutical compounds due to its versatile properties and reactivity.

InChI:InChI=1/C5H11N3O/c6-5(9)4-3-7-1-2-8-4/h4,7-8H,1-3H2,(H2,6,9)

84501-64-4 Relevant articles

Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide

Ingham, Richard J.,Battilocchio, Claudio,Hawkins, Joel M.,Ley, Steven V.

, p. 641 - 652 (2014)

Here we describe the use of a new open-s...

PROCESS FOR THE PREPARATION OF A CHIRAL PIPERAZINE-2-CARBOXYLIC ACID

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Page/Page column 13; 14, (2021/11/06)

The invention relates to a novel process...

Piperazine additions to C60 - A facile approach to fullerene substitution

Butts, Craig P.,Jazdzyk, Mikael D. S.

, p. 1209 - 1215 (2007/10/03)

A range of fullerene monoadducts can be ...

The preparation and structures of non-hydrocarbon functionalised fullerene-diamine adducts

Butts, Craig P.,Jazdzyk, Mikael

, p. 1530 - 1531 (2007/10/03)

Addends based on C2-substituted piperazi...

84501-64-4 Process route

pyrazinamide
98-96-4

pyrazinamide

2-aminocarbonylpiperazine
84501-64-4

2-aminocarbonylpiperazine

Conditions
Conditions Yield
With palladium 10% on activated carbon; hydrogen; In ethanol; water; at 100 ℃; Pressure; Temperature; Solvent; Time;
95%
With hydrogen; palladium on activated charcoal; In ethanol; at 85 ℃; for 5h; under 15001.2 Torr;
82.2%
With hydrogen; palladium dihydroxide; In ethanol; water; at 50 ℃; for 2h; under 2585.7 Torr;
64%
With palladium on activated charcoal; ethanol; Hydrogenation;
With palladium 10% on activated carbon; water; hydrogen; at 40 ℃; for 18h; under 15001.5 Torr; Sealed tube;
1,4-dibenzyl-piperazine-2-carboxylic acid amide
188847-59-8,188847-60-1

1,4-dibenzyl-piperazine-2-carboxylic acid amide

2-aminocarbonylpiperazine
84501-64-4

2-aminocarbonylpiperazine

Conditions
Conditions Yield
With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃;
95%

84501-64-4 Upstream products

  • 98-96-4
    98-96-4

    pyrazinamide

  • 188847-59-8
    188847-59-8

    1,4-dibenzyl-piperazine-2-carboxylic acid amide

84501-64-4 Downstream products

  • 31321-68-3
    31321-68-3

    (R)-piperazine-2-carboxylic acid

  • 147650-70-2
    147650-70-2

    (2S)-piperazine-2-carboxylic acid

  • 112257-24-6
    112257-24-6

    tert-butyl 3-(aminocarbonyl)piperazine-1-carboxylate

  • 83898-63-9
    83898-63-9

    hexahydro-3,3-dimethylimidazo[1,5-a]pyrazin-1(5H)-one

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