Chloramphenicol palmitate
- Name Chloramphenicol palmitate
- CAS 530-43-8
- Purity 99%
Product Details
Quality products?make an important contribution to long-term revenue and profitability. Top Quality Chinese Manufacturer supply 530-43-8 Chloramphenicol palmitate
1.What is the Chloramphenicol palmitate ?
white crystals
Chloramphenicol palmitate is an orally bioavailable ester prodrug form of the antibiotic chloramphenicol. It is hydrolyzed in the small intestine to release chloramphenicol. Formulations containing chloramphenicol palmitate were previously used in the treatment of severe bacterial infections.
2.What is the CAS number for Chloramphenicol palmitate ?
The CAS number of Chloramphenicol palmitate is 530-43-8.
3.What are another words for Chloramphenicol palmitate ?
Synonyms?for?Chloramphenicol palmitate 530-43-8:Hexadecanoicacid, (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl ester(9CI);Palmitic acid, ester with chloramphenicol (6CI);Chlorambon;Chloramphenicol monopalmitate;Chloramphenicol monopalmitate(ester);Chloramphenicol palmitate (ester);D-(-)-Chloramphenicolpalmitate;
4.What is Chloramphenicol palmitate (530-43-8) used for?
Chloramphenicol palmitate is prepared by acylation of chloramphenicol with palmitic acid. Although chloramphenicol palmitate is a more hydrophobic drug which should enhance bioavailability, the primary advantage of the ester is to mask the taste of chloramphenicol in oral formulations. Chloramphenicol palmitate is significantly less active than chloramphenicol but acts as a prodrug, being readily hydrolysed by acid and esterase in the gut to release chloramphenicol.
InChI:InChI=1/C27H42Cl2N2O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-24(32)37-20-23(30-27(34)26(28)29)25(33)21-16-18-22(19-17-21)31(35)36/h16-19,23,25-26,33H,2-15,20H2,1H3,(H,30,34)/t23-,25-/m1/s1
Relevant articles related to Chloramphenicol palmitate:
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Article |
Source |
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The preparation and isolation of chloramphenicol palmitate in toluene |
Daugs, Edward D. , p. 301 - 304 (2000) |
|
Substrate imprinted lipase nanogel for one-step synthesis of chloramphenicol palmitate |
Wang, Rui,Zhang, Yifei,Huang, Jinhai,Lu, Diannan,Ge, Jun,Liu, Zheng supporting information, p. 1155 - 1158 (2013/06/27) |
|
Enzymatic regioselective production of chloramphenicol esters |
Bizerra, Ayla M.C.,Montenegro, Tasso G.C.,Lemos, Telma L.G.,De Oliveira, Maria C.F.,De Mattos, Marcos C.,Lavandera, Iván,Gotor-Fernández, Vicente,De Gonzalo, Gonzalo,Gotor, Vicente supporting information; experimental part, p. 2858 - 2862 (2011/05/12) |
5.Buy Chloramphenicol palmitate with the best price .
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